Predictive Role of PR Segment, Q Wave Duration and Amplitude, ST Segment, U Wave and Sinus Rhythm in Preeclamptic Pregnant Women in the Third Trimester of Pregnancy
DOI:
https://doi.org/10.62951/ijhsb.v2i1.325Keywords:
Preeclampsia, PR Segment, Q Wave duration and amplitude, ST Segment, U wave and Sinus rhythmAbstract
Early detection and prediction of preeclampsia are crucial to prevent severe complications and ensure timely interventions, Specific ECG patterns, including PR segment, Q wave duration and amplitude, ST segment, U wave, and sinus rhythm were under study for their potential indicators of preeclampsia. This study aims to investigate the predictive role of these ECG patterns in preeclamptic pregnant women in the third trimester of pregnancy. Fourty (40) consenting pregnant women were recruited from St. Philomina Catholic Hospital, Edo State, Nigeria. These subjects consisted of twenty (20) normotensive and twenty (20) preeclamptic pregnant women in their third trimester of pregnancy. After the subjects were identified and recruited into the study, they were taken to the laboratory where their vital signs was taken and their ECG patterns recorded with ECG machine. Data obtained from this study were analysed using Graph Pad Prism 9. Results generated were expressed as mean ± SEM and a P-value of ≤ 0.05 were considered statistically significant. results from this present study show no significant differences were observed in the P-R segment, R-R interval, Q wave duration, Q wave amplitude The study underscores the multifactorial nature of cardiovascular changes in preeclampsia and highlights the potential of ECG parameters in aiding early detection, risk stratification, and management of the condition, despite parameters showing no significant differences. However, PR Segment, Q Wave duration and amplitude, ST Segment , U wave and Sinus rhythm cannot be used to predict preeclampsia
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References
Abduazimovich, K. S., & Rashidbekovna, S. M. (2023). Current understanding of the development and pathogenesis of preeclampsia. Central Asian Journal of Medical and Natural Science, 4(5), 587-592.
Betai, D., Ahmed, A. S., Saxena, P., Rashid, H., Patel, H., Shahzadi, A., ... & Nazir, Z. (2024). Gender disparities in cardiovascular disease and their management: A review. Cureus, 16(5).
Bisson, C., Dautel, S., Patel, E., Suresh, S., Dauer, P., & Rana, S. (2023). Preeclampsia pathophysiology and adverse outcomes during pregnancy and postpartum. Frontiers in Medicine, 10, 1144170.
Ceballos-Juárez, R. G., Pichardo-Carmona, E. Y., Mendieta-Zerón, H., Echeverría, J. C., & Reyes-Lagos, J. J. (2023). Multiscale asymmetry reveals changes in the maternal short-term heart rate dynamics of preeclamptic women during labor. Technology and Health Care, 31(1), 95-101.
Chaiworapongsa, T., Chaemsaithong, P., Korzeniewski, S. J., Yeo, L., & Romero, R. (2014). Pre-eclampsia part 2: Prediction, prevention and management. Nature Reviews Nephrology, 10(9), 531-540.
Clark, A. R., Fontinha, H., Thompson, J., Couper, S., Jani, D., Mirjalili, A., ... & Stone, P. (2023). Maternal cardiovascular responses to position change in pregnancy. Biology, 12(9), 1268.
Clasen, L., Angendohr, S., Becher, S., Bartsch, B., Enkel, S., Meyer, C., ... & Klöcker, N. (2023). Cardiac ischemia and reperfusion in mice: A comprehensive hemodynamic, electrocardiographic and electrophysiological characterization. Scientific Reports, 13(1), 5693.
Dahn, R. (2023). Deciphering the molecular mechanisms of endothelial cell dysfunction in preeclampsia: The impact of TNF-α and interleukins elevated in preeclamptic subjects on endothelial monolayer disruption vs. cell state changes. The University of Wisconsin-Madison.
de Alencar Neto, J. N., de Andrade Matos, V. F., Scheffer, M. K., Felicioni, S. P., De Marchi, M. F. N., & Martínez-Sellés, M. (2024). ST segment and T wave abnormalities: A narrative review. Journal of Electrocardiology.
Duley, L. (2009, June). The global impact of pre-eclampsia and eclampsia. Seminars in Perinatology, 33(3), 130-137. WB Saunders.
Fonkou, R. F., & Savi, M. A. (2023). Heart rhythm analysis using nonlinear oscillators with Duffing-type connections. Fractal and Fractional, 7(8), 592.
Goldberger, A. L., Goldberger, Z. D., & Shvilkin, A. (2023). Goldberger's clinical electrocardiography-e-book: A simplified approach. Elsevier Health Sciences.
Khan, J. A., Ashraf, A., Fayaz, F., & Qureshi, W. (2023). Electrocardiographic pattern in hypertensive disorders of pregnancy. International Journal of Research in Medical Sciences, 11(11), 4154.
Koivula, K. (2023). Electrocardiogram in assessing mortality in acute coronary syndromes.
Kotsialou, Z., Makris, N., & Gall, S. (2024). Fundamentals of the electrocardiogram and common cardiac arrhythmias. Anaesthesia & Intensive Care Medicine.
Nandini, B. N. (2011). Study of ECG patterns in 1st, 2nd and 3rd trimesters of pregnancy (Doctoral dissertation, BLDE [Deemed to be University]).
Paswan, S. K., Singh, B. K., & Jaisawal, A. A. (2023). Study of electrocardiographic changes in second and third trimester of pregnant women at Government Medical College (GMC) Purnea, Bihar. International Journal of Academic Medicine and Pharmacy, 5(5), 1759-1764.
Pegorie, C., Liu, B., Thilaganathan, B., & Bhide, A. (2024). Antenatal noninvasive fetal electrocardiography: A literature review. Maternal-Fetal Medicine, 6(3), 178-189.
Tribhuvanam, A., Shrestha, P., & Ghimire, S. (2020). Electrocardiographic patterns in normal pregnancy: A pictorial review. Journal of Nepal Medical Association, 58(221), 95–100.
Varaganti, S., Manisha, R. L., & Muvvala, S. (2024). From waves to diagnoses: Decoding electrocardiogram for improved cardiac care. Archives of Medicine and Health Sciences, 12(1), 88-96.
Vata, V. K., Sharma, N., & Singh, P. (2015). Sample size determination in clinical studies. Indian Journal of Medical Research, 142(3), 215–221.
Yang, C., Baker, P. N., Granger, J. P., Davidge, S. T., & Tong, C. (2023). Long-term impacts of preeclampsia on the cardiovascular system of mother and offspring. Hypertension, 80(9), 1821-1833.
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